MK2866, popularly known as Ostarine, is an SARM developed by GTx for the treatment and prevention of muscle wasting. At present, clinical trials are conducted to test its capability in preventing atrophy, sarcopenia, and cachexia as well as for Hormone or Testosterone Replacement Therapy.
As a research chemical, Ostarine belongs to a group of chemicals called as Selective Androgen Receptor Modulators or SARMS. These chemicals perform selective anabolic activity on particular androgen receptors only, hence their name. As compared to testosterone as well as other pro hormones and anabolic steroids, the benefit of using SARMS is that they do not have any androgenic activity in the non-skeletal muscle tissues.
This substance is effective not just in maintaining lean body mass but in increasing it as well. It is most of the time described as or called S1, but this is incorrect since S1 is an SARM that was formed quite early, and further development has been done.
What SARMs Can Do For Your Muscle
SARMs bind to the androgen receptor as well as demonstrate osteo (bone) and myo (muscular) anabolic activity. Activation and binding to the androgen receptor affect the genes expression and protein synthesis is increased, thus building muscle. MK2866 causes muscle growth in the same way as the steroids do. However, as compared to testosterone as well as other prohormones and anabolic steroids, they do not produce the growth effect in the prostate and in other secondary sexual organs.
The Effects of Ostarine Anabolic Activity
The anabolic activity of Ostarine affects the muscle tissue only. It does not only provide treatment for muscle wasting disease, but it is also very effective in building muscles for athletes and bodybuilders. It is also an agent that reduces atrophy during the recovery period after serious surgery.
Studies Conducted to Prove Ostarine’s Effectiveness
GTx has conducted several clinical trials and efficacy studies that involve 600 subjects. One study, the 4 month Phase IIb clinical trial that involves 159 participants, was conducted to prove MK2866’s ability to increase the total lean mass and to increase the muscle strength. Almost all of the participants show an increase in their lean body mass (LBM) as well as strength levels.
The Uses of Ostarine
1.Lean Muscle Gains (bulking)
As mentioned above, its primary function is to increase lean body mass. The increase in muscle is different with the one you can gain from using steroids. The gain you will get is exclusively lean muscle mass only. Since the substance lacks shutdown as compared to steroids, a PCT period is not required and the muscle gained will remain once the cycle is completed.
A 25mg dose of Ostarine for four to six weeks is recommended for achieving the lean body mass that you want. This will produce six bounds or three kilograms of lean mass.
Users can take as much as 36 mg (This is recommended only for those who weigh 210lbs.) for 8 weeks. However, the possibility for suppression from this dose is higher and users should look into a PCT protocol after completing the cycle.
Most of the Ostarine 25mg are available in 30ml bottles. A 17.5mg dose each day will provide a six-week cycle.
2.Losing Body Fat (Cutting)
MK2866 is used in a cutting protocol to maintain muscle mass while reducing calories. Losing one’s hard-earned muscle mass is disheartening. The drop in hormone levels with lack of calories is an ideal catabolic environment for loss of muscle tissue. The dieters can reduce calories without worrying about the strength or muscle loss. This substance has shown nutrient partitioning impacts among users.
A four to six weeks protocol with 12.5 to 15mg dosing is good for cutting using MK2866 without experiencing any suppression or side effects.